The IDENTIFY study: the investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer – a multicentre observational study

Objective To evaluate the contemporary prevalence of urinary tract cancer (bladder cancer, upper urothelial [UTUC] and renal cancer) in patients referred to secondary care with haematuria, adjusted for established patient risk markers geographical variation. Patients Methods This was an international multicentre prospective observational study. We included aged ?16 years, suspected cancer. a known or previous urological malignancy were excluded. estimated bladder UTUC, prostate cancer; stratified by age, type sex, smoking. used multivariable mixed-effects logistic regression adjust smoking, hospitals, countries. Results Of 11 059 assessed eligibility, 10 896 from 110 hospitals across 26 The overall (n = 2257) 28.2% (95% confidence interval [CI] 22.3–34.1), 1951) 24.7% CI 19.1–30.2), UTUC 128) 1.14% 0.77–1.52), 107) 1.05% 0.80–1.29), 124) 1.75% 1.32–2.18). odds ratios model all cancers were: age 1.04 1.03–1.05; P < 0.001), visible haematuria 3.47 2.90–4.15; male sex 1.30 1.14–1.50; smoking 2.70 2.30–3.18; 0.001). Conclusions A better understanding population is required inform clinical guidelines. are first report care, Bladder most prevalent disease. Visible strongest predictor